Run your exact process on TFFi, with your own material, and compare the results head to head against your existing equipment. We bring the system and the engineer. You bring the process, run exactly as you run it today.
No hardware or engineering cost · Your process, unchanged · Your data · A like-for-like comparison
Every equipment vendor makes claims. We would rather show you.
Spec sheets and case studies are built on someone else's molecule, in someone else's facility. They tell you what a system did for a different product, not what it will do for yours. Filterability charts, shear data, yield figures, they are all someone else's numbers until they are run on your material. The Prove-It program removes the guesswork: we put TFFi on your bench, run your own process head to head with your existing equipment, and let your data settle it. The only benchmark that matters is your own.
TFFi was built for the modalities conventional equipment quietly fails. So we are not chasing easy wins. We want the hardest processes and the most fragile products, the runs where yield disappears and no one is quite sure why. Every Prove-It sharpens TFFi and our understanding of fragile-modality processing. You get your data. We get a harder problem to solve. The field moves forward.
We want
Viral vectors, LNPs, and cell and gene therapy products that conventional pumping quietly damages.
High-concentration, high-stress runs where conventional TFF starts to break down.
The recoveries that fall short for reasons that turn out to be mechanical, not chemical.
We run your process exactly as it is today, on TFFi, and measure it against the same process on your existing equipment. No tuning, no process changes, only the system is different.
We agree the process under test, put an NDA in place, and plan the run around your product.
Alphinity ships a single-use TFFi system and a tech-transfer engineer to your site. At no cost to you.
Day one, set up and verify. Day two, run your own process, unchanged, on the TFFi system.
A joint Prove-It report puts the TFFi run side by side with the same process on your existing equipment.
Not a benchmark from someone else's molecule. Evidence from yours.
Your process and material on TFFi, measured directly against the same run on your existing equipment.
The system, the consumables, and the Alphinity engineer are all provided. You contribute the material and the facility.
One shared, jointly approved record of what happened and what it means, ready to take to your team.
The first team to prove TFFi in a given modality earns a co-publication opportunity and a benefit on a future system.
Clear by design, so your team knows exactly what they are agreeing to.
If your product is fragile or your process is intensified, this is where pump and system design start to cost you yield.
Tell us about your product and process. We will scope a Prove-It campaign and show you what TFFi does with your own material.
Request a Prove-It