Pinch Valve Series
ARTēVA® is Alphinity's family of stainless steel pinch valves for bioprocessing. Three actuation options (electric, pneumatic, and manual) built on one proven 316L stainless steel pinch head. Single-use tubing. Reusable mechanism. Over 30 years of sanitary valve manufacturing experience.
Three Actuation Options
Every ARTēVA® valve shares the same 316L stainless steel encapsulated pinch head and single-use tubing compatibility. Choose your actuation based on your process requirements: electric precision, pneumatic speed, or manual simplicity.
Electrically actuated · Stepper motor control
Best for: Automated skids, perfusion, filtration control, media/buffer transfer
Pneumatically actuated · Fast uniform closure
Best for: High-throughput commercial production lines with existing pneumatic infrastructure
Manual actuation · Tool-free operation
Best for: Lab-scale development, benchtop setups, mobile carts, small-scale sterile operations
Core Design
Every ARTēVA® variant shares the same fundamental architecture: a reusable 316L stainless steel encapsulated pinch head with single-use tubing. The actuation changes. The reliability doesn't.
Encapsulated, hygienic, corrosion-resistant, and autoclavable. Built for repeated use, cleaning, and long-term performance in demanding bioprocess environments.
Consistent sealing geometry across thousands of cycles. No variation, no guesswork: the same reliable pinch every time.
Works with silicone, TPE, braided and reinforced single-use tubing from ¼″ to 1″ ID. No proprietary consumables, no vendor lock-in.
Single-use tubing swaps in seconds without tools. Sterility maintained. Operator time minimized. No cleaning validation required.
Clear operator feedback at a glance. Know the valve state without instrumentation, essential for manual operations and visual process checks.
Produced in the United States by Alphinity's stainless steel valve division, with over 30 years of experience designing and manufacturing sanitary bioprocessing components.
Where ARTēVA® works
ARTēVA® valves are used across upstream and downstream bioprocessing, anywhere a reliable, hygienic pinch valve is needed with single-use tubing compatibility.
Media and buffer transfer, cell culture feed lines, perfusion circuits, and bioreactor inlet/outlet control. The reusable pinch mechanism handles repeated cycling with consistent compression.
Filtration and chromatography systems, harvest and collection paths, viral inactivation hold steps, and final fill workflows. Single-use tubing eliminates cross-contamination between batches.
Sampling points, bypass operations, and diversion paths where quick, reliable switching is needed without contaminating the main product stream.
Process development, screening, and small-scale sterile operations. The Manual variant requires no infrastructure: just clamp on, connect tubing, and operate.
Valve Selector
From simple manual control to full digital automation, find the variant that fits your application, scale, and infrastructure.
Not sure which variant fits? Talk to an engineer →
Part of the Alphinity Platform
ARTēVA® pinch valves integrate directly into systems built around PIXER® pumps and VannX™ diaphragm valves, covering every flow control requirement from gentle product transfer to precision pressure control.
Pump Technology
Ultra-low shear positive displacement pumping for fragile biologics and viscous formulations. Pairs with ARTēVA® for complete flow path control.
Precision Valve Technology
±0.3 PSI proportional pressure control. 24V DC electric, no compressed air. Complements ARTēVA® where precision TMP control is required.
Integrated Systems
ARTēVA®, PIXER®, and VannX™ combined into fully integrated, automation-ready bioprocessing systems. Built around your process.
Why ARTēVA®
The stainless steel pinch head is built to last thousands of cycles. The tubing is disposable. That combination delivers the sterility assurance of single-use with the cost efficiency of a reusable instrument, without compromise.
Fully disposable pinch valves replace the entire mechanism with each batch, driving high consumable costs over time. ARTēVA®'s reusable stainless steel head significantly reduces cost of ownership: only the tubing is replaced.
Yes. The 316L stainless steel pinch head is autoclavable. The single-use tubing is replaced between runs, maintaining sterility without cleaning validation.
ARTēVA® is compatible with ¼″ to 1″ ID tubing across silicone, TPE, braided, and reinforced formats. No proprietary tubing required.
ARTēVA® is manufactured in the United States by Alphinity's stainless steel valve division. Over 30 years of experience producing sanitary bioprocessing components.
Get Started
Talk to our engineers about your application: tubing size, cycle frequency, actuation preference, and integration requirements. We'll specify the right variant.